Well there will prolly be more experienced players answere but from my poin of view(isen player that farms onyx regulary) i would say no. I dont know if it is diffrent on Janius(since i dont know where you play) but here you gear means that you have around 3.5k Pdef maybe even less, about 2k Psy(if you fully specced psy ofc) and that leads to this>>> about a reduction of dmg by around 1k(psy-shield) and mobs do about 5-8k normal and 10-16k crit vs your armor which means you get 4-7k normal and 9-15k crits form the mobs. If you now dont have about 100k hp, you get shredd into pieces as soon as you get aggro of the full room.
But again maybe im exaggerate it and you will be fine but from what you listed it sounds unlikely.